Methoxyamine HCl ( TRC102,TRC 102,TRC-102 )

Catalog No. M22875 CAS No. 593-56-6

Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Methoxyamine HCl
Note

Research use only, not for human use.
Brief Description

Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis.
Description

Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity.?This agent may potentiate the anti-tumor activity of alkylating agents.
Synonyms

TRC102,TRC 102,TRC-102
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

593-56-6
Formula Weight

83.51
Molecular Formula

CH6ClNO
Purity

>98% (HPLC)
Solubility

Water:Soluble
SMILES

CON.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. She MR, Guo KY, Niu XQ, Lu XX. [Effects of manumycin combined with methoxyamine on apoptosis in myeloid leukemia U937 cells]. Ai Zheng. 2008 Aug;27(8):835-9. Chinese. PubMed PMID: 18710617.

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