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Methoxyamine HCl

CAS No. 593-56-6

Methoxyamine HCl( TRC102,TRC 102,TRC-102 )

Catalog No. M22875 CAS No. 593-56-6

Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Methoxyamine HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis.
  • Description
    Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity.?This agent may potentiate the anti-tumor activity of alkylating agents.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    TRC102,TRC 102,TRC-102
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    593-56-6
  • Formula Weight
    83.51
  • Molecular Formula
    CH6ClNO
  • Purity
    >98% (HPLC)
  • Solubility
    Water:Soluble
  • SMILES
    CON.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. She MR, Guo KY, Niu XQ, Lu XX. [Effects of manumycin combined with methoxyamine on apoptosis in myeloid leukemia U937 cells]. Ai Zheng. 2008 Aug;27(8):835-9. Chinese. PubMed PMID: 18710617.
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